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Michael J. DeProfio

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Joyce Funeral Home

245 Main Street
Waltham, MA 02453
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Memories & Candles

“Ill always remember Mike as a good man and friend. We always had time to talk when we bumped into each other at the Stop & Shop in Waltham or any...Read More »
1 of 14 | Posted by: Buddy Casella - N. Billerica, MA

“Michael, you'll always missed. Rest in everlasting peace. ”
2 of 14 | Posted by: Emanuele Gandolfo - Revere, MA

“A neighbor back in the 1960's. Many years later was in Waltham and saw Michael at church. We recognized one another and spoke of Smart St. Nice,...Read More »
3 of 14 | Posted by: Sheila (Caisey/McCarthy) Durkin - MA

“Joanne , so very sorry for your loss. Our thoughts and prayers are with you. ”
4 of 14 | Posted by: Bob and Doreen Bevington - MA

“Joanne and the entire DeProfio family my sincere condolences on Mike's passing. In the over 50 years of our friendship did I ever hear him complain...Read More »
5 of 14 | Posted by: Paul Bergeron - Jupiter, FL

“Joanne and Family, We were so saddened to hear about Mike, He will be missed.He was fun loving and both my husband...Read More »
6 of 14 | Posted by: Loraine Kelley - Family Friend

“Joanne and Family I was so sorry to hear of Michael passing....so sad....you two were great together. May all ur memories stay in ur heart forever...Read More »
7 of 14 | Posted by: Bob & Mary ann McGovern - Waltham

“To my dear brother, Mike. You will be missed by so many people. Give Dad, and Jeff a kiss from me. Love you always. XO ”
8 of 14 | Posted by: Sue Fisher - Gardner, MA

“Oh, my dear cousin, I have a lifetime of "Mikey" memories: growing up with our cousins always around; you teaching me to dive at the MDC pool; skiing...Read More »
9 of 14 | Posted by: Judy O'Neil - Waltham, MA

“Dear Mike, As much as we always enjoyed your company and your great sense of humor, we admire you even more. You lived your life and faced all its...Read More »
10 of 14 | Posted by: Judy and John Rando - New Castle, NH

“Mike, your smile, love of life and sometimes bad jokes will be missed. Thank you for the best gift ever, your children. Rest easy my friend. ”
11 of 14 | Posted by: Maureen Salazar - Uxbridge, MA

“NOW THAT YOU ARE IN THE GLORY OF THE LORD, I KNOW THAT YOU ARE VERY PEACEFUL, BECAUSE HERE ON EARTH YOU ALWAYS DID GOOD AND YOU STRIVED TO BE HAPPY...Read More »
12 of 14 | Posted by: SANDRA MORAN - ASHLAND, MA

“Mike you are now in eternal peace. God has blessed you.RIP ”
13 of 14 | Posted by: Joanne DeProfio - Bluffton, SC

“He'll truly be missed. I enjoyed spirited conversations with Michael and our golf games. ”
14 of 14 | Posted by: Edmund Kelly - Lee, MA - Family


Bluffton, SC – Mr. Michael J. DeProfio, of Bluffton, South Carolina, formerly of Waltham, died at home on Tuesday, June 23, 2020. He was 71.

Mike was born on September 21, 1948, a son of Phyllis (Murphy) DeProfio of Waltham and the late Peter J. DeProfio. He was raised and educated in Waltham and was a graduate of Waltham High School and Bentley College.

He had worked as an accountant and lived in Waltham, Newton, Westborough and Ashland before moving to Bluffton two years ago.

Prior to moving Mike was a member of the Knights of Columbus at Our Lady Comforter of the Afflicted Parish in Waltham. He adapted quickly to his new home in Bluffton and made new friendships during his weekly cribbage games at Hilton Head's senior center. He also indulged his passion for golf at every opportunity.

Mike leaves his wife, Joanne (O'Reilly) DeProfio; his children, Peter J. DeProfio of Mendon and Christine M. Arthur (Sam) of Hopedale; his mother, Phyllis (Murphy) DeProfio of Waltham; his grandchildren, Deven and Cedric Arthur and Andrew Gabbard; his great-granddaughter, Scarlett Gabbard; his siblings, Steven DeProfio (Marie) of Waltham, Susan Fisher (Dale) of Gardner, and Sally Chairolanza (Paul) of Mansfield, and many nieces, nephews and their families.

Calling hours for Mike will be held in The Joyce Funeral Home, 245 Main Street (Rte. 20), Waltham on Thursday, July 2nd from 4 to 7 p.m. [Those over 60 and those with underlying health conditions are welcome to visit from 4 to 5 p.m. and others from 5 to 7 p.m.]

His Funeral Mass will be celebrated at 10 a.m. Friday in Our Lady Comforter of the Afflicted Church, 880 Trapelo Road, Waltham. Burial will be in Calvary Cemetery, Waltham.

In lieu of flowers, donations in Mike's memory may be made to Saint Jude Children's Research Hospital, 501 St. Jude Place, Memphis, Tennessee 38105.